Before taking isotretinoin,
tell your doctor and pharmacist if you are allergic to isotretinoin, parabens, or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially carbamazepine (Tegretol), demeclocycline (Declomycin), doxycyline (Monodox, Vibramycin, and others), minocycline (Minocin), oxytetracycline (Uri-Tet), tetracycline (Achromycin V), vitamin A, and other vitamins and herbal products. Do not take any vitamin supplements that contain vitamin A to avoid possible harmful reactions.
tell your doctor if you have or have ever had diabetes, liver disease, pancreatitis, a high amount of triglycerides (fats) in your blood, a family history of high triglycerides in the blood, or depression.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Isotretinoin may make your skin sensitive to sunlight.
isotretinoin may cause intracranial hypertension, especially when it is taken with tetracycline. Intracranial hypertension is a condition caused when the pressure in the blood vessels of the brain increases or when the brain swells. Symptoms of intracranial hypertenstion include severe headache, upset stomach and vomiting, and changes in vision. If you have any of these symptoms, call your doctor immediately.
be aware that this medicine may affect your night vision. Be cautious when driving or operating any machinery after dark.
hair removal by waxing and laser procedures to the skin should be avoided while taking isotretinoin and for 6 months after stopping isotretinoin. These procedures may cause scarring.
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