Combigan [Brimonidine and Timolol Ophthalmic] is a prescription eye drop that is used in the treatment of glaucoma and ocular hypertension, a condition that creates high pressure inside the eyes. Brimonidine belongs to the group of drugs known as alpha – agonists. It works by reducing the pressure in the eyes by reducing the amount of fluid present. Timolol on the other hand is a beta blocker. This medicated eye drop may also be used for purposes other than the ones mentioned here.
How to use
Combigan [Brimonidine and Timolol Ophthalmic] is an eye drop and it should be administered according to the doctor’s advice. It is important that the patient washes his hands before application. The head must be tilted back slightly and the lower lid of the eye pulled down. The dropper that comes along with the eye drop must be held above the eye with the tip down. A drop should be squeezed out onto the eye and the eye closed thereafter. The corner of the eyes near the nose is then to be pressed gently with a finger for a minute in order to prevent the eye drop from getting out.
Care must be taken to see that the dropper tip does not touch any surface, including the patient’s hands or eyes. This will prevent contamination of any kind. The eye drop should not be used while the patient is still wearing contact lenses.
Side Effects
Combigan [Brimonidine and Timolol Ophthalmic] may cause certain side effects in some patients. Most of them are not serious and are known to go away on their own. The following are such side effects:
Blurred vision and dry eyes
Tiredness and weakness
Upset stomach, nausea
Drowsiness
Sensitivity to light
Mild stinging, itching or burning of the eyes
Mildly puffy or swollen eyes
Sore throat, cough
Headache
Metallic taste in the mouth
Dry nose
Drug Interaction
Combigan [Brimonidine and Timolol Ophthalmic] may cause drug interactions when co – administered with certain other medications. Special mention should be made in the case of the following medications as they can be extremely dangerous if used along with the eye drop: MAO inhibitors such as furazolidone, isocarboxazid, phenelzine, procarbazine, selegiline, tranylcypromine, linezolid, procarbazine or tranylcypromine.
Other than these, the doctor should be aware if the patient is using any of the following medications before prescribing Combigan [Brimonidine and Timolol Ophthalmic]: certain diabetic medications (sulfonylureas, insulin), epinephrine, calcium channel blockers like diltiazem or verapamil, theophylline, quinidine, epinephrine, drugs for high blood pressure (reserpine, methyldopa, clonidine) and antidepressants like SSRIs and tricyclics.
Uses
Combigan [Brimonidine and Timolol Ophthalmic] is prescribed for use intreating certain eye conditions such as glaucoma and ocular hypertension.
Storage
Combigan [Brimonidine and Timolol Ophthalmic] is to be kept in a cool and dark place away from excessive heat and sunlight.
Precaution
People with asthma, COPD, slow heartbeats, heart failure, heart disease or AV block should let the doctor know of their condition before using Combigan [Brimonidine and Timolol Ophthalmic].
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