Mirtazapine adds to the sedating effects of alcohol and other drugs that can cause sedation such as the benzodiazepine class of anti-anxiety drugs (e.g., Valium, Ativan, Klonopin, Xanax), the narcotic class of pain medications and its derivatives (e.g., Percocet, Vicodin, Dilaudid, Codeine, Darvon), the tricyclic class of antidepressants (e.g., Elavil, Tofranil, Norpramin), certain antihypertensive medications (e.g., Catapres, Inderal), and some antihistamines (e.g., Benadryl; Atarax; Vistaril).
Fluvoxamine (Luvox) may increase the levels of mirtazapine in the blood which may lead to increased side effects from mirtazapine.
Because of the possibility of developing an increased body temperature (hyperpyrexia), high blood pressure, or seizures, use of mirtazapine is not recommended together with monoamine oxidase inhibitors (MAO's), such as furazolidone (Furoxone), phenelzine (Nardil), procarbazine (Matulane), selegiline (Carbex), or tranylcypromine (Parnate). An interval of 14 days is recommended between stopping MAO inhibitor therapy and starting mirtazapine and vice versa. |
Anti-Narcoleptic
