The active ingredient of Solifenacin generic is Solifenacin succinate. It belongs to a class of drugs known as anticholinergic or antimuscarinic receptor antagonist. Solifenacin generic [Solifenacin succinate] is used for the treatment of overactive bladder symptoms such as frequent urination, leaking accidents and sudden or frequent urges to urinate. Solifenacin generic [Solifenacin succinate] works by blocking cholinergic or muscarinic receptors, found on the muscle wall of the bladder. Due to the presence of these receptors the natural body chemical known as acetylcholine acts on these receptors and makes the muscles of the bladder to contract which cause overactive bladder symptoms. By blocking these receptors, the chemical acetylcholine cannot act on the muscle wall of the bladder and thereby help relieve the symptoms. It is available as an oral medication in a form of tablets with different strengths of 5mg and 10mg.
How to use
Solifenacin generic [Solifenacin succinate] tablets should be taken once daily with or without food.
Tablets should be taken at the same time each day to maintain even level in blood.
The initial recommended dose for overactive bladder treatment is 5mg once in a day. The dosage can be increased to a maximum of 10mg a day.
Patients with kidney disorder should not exceed the dosage beyond 5mg per day.
Side Effects
Most common Solifenacin generic [Solifenacin succinate] side effects indicated using the medication are dry mouth, constipation, blurred vision, nausea, urinary tract infections (UTI), indigestion or heartburn.
Other common side effects reported are upper abdominal pain, vomiting, sore throat, flu, dizziness, dry eyes, fatigue, swelling or water retention in calves, ankles and feet, cough and high blood pressure.
Some serious side effects indicated are severe constipation, worsening of glaucoma, difficulty passing urine, confusion, depression and allergic reactions like unexplained rash and swelling, hives, itching and wheezing.
Drug Interaction
Concomitant use of acetylcholinesterase inhibitor and Solifenacin generic [Solifenacin succinate] can make both the medications less effective.
Concomitant use of anticholinergic drug and Solifenacin generic [Solifenacin succinate] may increase the risk of side effects of Solifenacin succinate because Solifenacin generic [Solifenacin succinate] is also an anticholinergic medication.
Concomitant use of antifungal or antibiotic drugs and Solifenacin generic [Solifenacin succinate] may increase the level of Solifenacin succinate in blood.
Concomitant use of Pramlintide and Solifenacin generic [Solifenacin succinate] can slow down the movement of food through the digestive tract which may increase the risk of constipation and nausea.
Concomitant use of Protease inhibitor and Solifenacin generic [Solifenacin succinate] can increase the level of Solifenacin succinate in blood.
Uses
Solifenacin generic [Solifenacin succinate] is used for the treatment of overactive bladder symptoms like sudden and frequent urges to urinate, leaking accidents and frequent urination.
Storage
Solifenacin generic [Solifenacin succinate] tablets should be stored at a temperature of 25oC (77oF), excursions permitted to 15o-30oC (59o-86oF).
Precaution
Patients with liver disease including liver failure, cirrhosis or hepatitis; irregular heart rhythm (arrhythmia); kidney disease including kidney or renal failure; glaucoma; digestive problem especially that causes the slowdown of food through digestive tract; difficulty passing urine; enlarged prostate and allergic to any food, dyes or preservatives should be cautious and consult the physician before administering the medicine.
Pregnant women and lactating mothers should consult the physician prior taking Solifenacin generic [Solifenacin succinate] medication.
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