Tiotropium bromide is the active ingredient present in the composition of Spiriva. Spiriva [Tiotropium bromide] is available in a form of an inhalation powder in a capsule. This capsule is not to be swallowed but the powder in the capsule is to be inhaled with special device only. Spiriva [Tiotropium bromide] is used to prevent bronchospasms caused by Chronic Obstructive Pulmonary Disease (COPD), including chronic bronchitis and emphysema. Spiriva [Tiotropium bromide] belongs to a class of drugs known as anticholinergics or antimuscarinics. By binding to specific receptors known as muscarinic receptors in the airway, Spiriva [Tiotropium bromide] helps to relax the smooth muscles. With just one dose a day, it helps to prevent bronchospasms and keep the airways open.
How to use
There is only one standard dosage of Spiriva [Tiotropium bromide] regardless of age, weight and medical condition. The recommended dose for Chronic Obstructive Pulmonary Disease (COPD) including emphysema and chronic bronchitis is 1 Spiriva [Tiotropium bromide] capsule (18mcg) to be inhaled once daily.
Capsules should be inhaled by or used by Spiriva HandiHaler, a special device with which the powder of the Spiriva [Tiotropium bromide] capsule is inhaled.
Side Effects
The most common side effects reported using Spiriva [Tiotropium bromide] medication are upper respiratory infections, dry mouth, sinus infection, sore throat and urinary tract infection.
Other common side effects indicated are abdominal pain, constipation, indigestion or heartburn, vomiting, muscle pain, yeast infection, nose bleeds and running nose.
Serious side effects indicated are worsening breathing problem, severe constipation and difficulty passing urine, arrhythmia, vision change, chest pain and allergic reactions.
Some rare side effects reported are leg pain, voice changes, unusual sensation such as burning, Gastro Esophageal Reflux Disease (GERD), hyperglycemia, high cholesterol, bone pain, depressions, shingles and cataracts.
Drug Interaction
When Spiriva [Tiotropium bromide] medication and Acetylcholinesterase Inhibitors medication are taken concurrently, both the medications become less effective.
When Spiriva [Tiotropium bromide] medication and Anticholinergic medication are taken concurrently, the risk of Spiriva [Tiotropium bromide] side effects increases as Spiriva [Tiotropium bromide] is also an anticholinergic medicine.
Uses
Spiriva [Tiotropium bromide] is used for the treatment of Chronic Obstructive Pulmonary Disease (COPD) and chronic bronchitis and emphysema which are also two kinds of COPDs.
Storage
Spiriva [Tiotropium bromide] should be stored at a temperature of 25oC (77oF), excursions permitted to 15o-30oC (59o-86oF). Protect from heat, direct sunlight and moisture.
Do not store Spiriva [Tiotropium bromide] capsule in the Spiriva HandiHaler.
Precaution
Since Spiriva [Tiotropium bromide] is an anticholinergic medication, patients suffering from glaucoma, bladder problem and prostate problem should not take this medication or else it may worsen the condition of the patient.
Spiriva [Tiotropium bromide] may slightly increase the risk of strokes. So precautions should be taken and physician should be consulted before administering the medication.
Spiriva [Tiotropium bromide] passes through breast milk, so lactating mothers should consult the physician before taking this medication.
Spiriva [Tiotropium bromide] may not be safe to use during pregnancy. So pregnant women or women planning to be pregnant should be cautious and inform the physician.
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