Vardenafil is the drug sold under the trade name of Levitra. Levitra’s active ingredient is Vardenafil HCL, available in a form of tablets. Vardenafil HCL [Levitra] is a drug commonly used for the treatment of Erectile Dysfunction (ED) also known as impotence. It is used for treating problems with obtaining or maintaining erection. Erectile dysfunction is the repeated inability to get or keep an erection firm enough for sexual intercourse. More blood in the penis means improved erection. PDE5 is a chemical present in the smooth muscle cell lining of the blood vessels of the penis which carries blood to penis. Vardenafil HCL [Levitra] is a PDE5 inhibitor which blocks PDE5 chemical which reverses the erection by flowing out the blood from the penis. Vardenafil HCL [Levitra] comes in different strengths such as 2.5mg, 5mg, 10mg and 20mg.
How to use
The recommended starting dosage of Vardenafil HCL [Levitra] for most of the patients is 10mg, once daily which has to be taken about an hour before sexual activity. It can be increased to 20mg according to the efficacy of the medicine or can be decreased to 5mg according to the adverse effects of the medicine.
The recommended starting dosage for geriatrics or elderly patients above 65 years of age is 5mg, once daily.
The recommended starting dosage for patients with liver disorder is 5mg, once a day which should not increase more than 10mg per day.
Vardenafil HCL [Levitra] should be administered once a day, with or without food and at any time of the day.
Side Effects
Common side effects indicated using Vardenafil HCL [Levitra] are headache, facial flushing, indigestion, stuffy or runny nose, flu like symptoms, sinusitis, increased level of creatine kinase in blood, nausea, accidental injury, dizziness and back pain.
Some rare side effects indicated are allergic reactions, angina pectoris, arthritis, blurred vision, diarrhea, high blood pressure, insomnia, prolonged erection without pain, prolonged and painful erection, sudden decrease or loss of hearing, unexplained rash, ringing in ears (tinnitus), temporary vision loss, blurred vision, urinary incontinence and vomiting.
Some serious or even fatal side effects indicated are heart attacks, serious irregular heart rhythms (arrhythmias), stroke and mini stroke, high blood pressure, bleeding within the brain or in spaces just outside the brain, bleeding in lungs and sudden death.
Drug Interaction
Vardenafil HCL [Levitra] when taken concomitantly for the patient with hypertension or benign prostatic hyperplasia (BPH) with alpha blockers, the patient may experience decreased blood pressure or low blood pressure.
Vardenafil HCL [Levitra] when taken by patients taking medicines to treat normal arrhythmia may end up with increased risk of very dangerous arrhythmias known as QT prolongation.
Vardenafil HCL [Levitra] when taken concomitantly with antibiotics or antifungals may increase the level of Vardenafil HCL in blood and increase the risk of side effects.
Vardenafil HCL [Levitra] when taken concomitantly with grapefruit juice may increase the level of the level of Vardenafil HCL in blood and increase the risk of side effects.
Vardenafil HCL [Levitra] when taken concomitantly with nitrates may cause dangerous hypotension.
Vardenafil HCL [Levitra] when taken concomitantly with protease inhibitors may increase the level of Vardenafil HCL in blood and increase the risk of side effects.
Uses
Vardenafil HCL [Levitra] is used to treat erectile dysfunction or impotence by treating problems with obtaining or maintaining erection.
Storage
Vardenafil HCL [Levitra] should be stored at a temperature between 15o-30oC (59o-86oF), away from heat and humidity.
Precaution
Patients with cardiovascular disease should be cautious and consult the physician before administering this medicine.
Avoid taking high fat meals because the medicinal effect will decrease.
Avoid taking the medication if the patient is having severe kidney failure or severe decreased liver functions.
Patients allergic Vardenafil should avoid taking this medication.
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