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  Mens Health» SILDENAFIL CITRATE - (sill DEN oh fill)

Buy Generic SILDENAFIL CITRATE at Discount | Generic Viagra Online at Cheap Prices

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Viagra Generic

Composition:

SILDENAFIL CITRATE - (sill DEN oh fill)

Common Brand:

Revatio

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Description
Sildenafil Citrate is used for erectile dysfunction treatment and also for the treatment of pulmonary arterial hypertension. Over 70 million people worldwide with impotency are believed to have some physical or medical cause which includes diabetes circulatory neurological or urological conditions. The leftover are due to psychogenic cause.
Sildenafil Citrate helps to release Nitric Oxide NO to the penis. Enzyme Guanylate cyclase binds with NO to increase the level of cyclic Guanosine Monophosphate cGMP which results in increased inflow of blood to penis causing erection.
cGMP specific Phosphodiesterase type 5 PDE5 is responsible for degradation of cGMP in the penis. Sildenafil acts as a competitive binding agent of PDE5 in penis resulting in increased cGMP and helps in better erection.
Sildenafil Citrate also relaxes the arterial wall which leads to decreased pulmonary arterial pressure and resistance. This helps in reducing the workload of right ventricle of the heart and improves symptoms of right-sided heart failure.


How to use
For erectile dysfunction Sildenafil Citrate of 25mg to 100mg has to be taken once in a day at least before 30 minutes but not more than 4 hours prior to sexual intercourse. An hour before is the most effective. A fat meal may delay the time of action of the drug. Grapefruit or its juice should be avoided while being treated with this medication.
The dosage of Sildenafil Citrate varies on medical conditions different therapies and response to therapies.
Consult the physician prior to medication.

Side Effects
The most common side effects of Sildenafil use are headache flushing indigestion upper abdominal pain and fullness nasal congestion excess sensitivity to light blurred vision loss of peripheral vision and cyanopsia seeing everything in tinted blue. Rare but serious adverse effects are found using Sildenafil Citrate which includes Priapism when the erection persists for more than 4 hours causing acute pain in penis severe hypertension and heart attack sever decreased liver function stroke and sudden hearing loss. In men for whom sexual intercourse is inadvisable should avoid this medication due to cardiovascular risk factor.

Drug Interaction
Patients taking Protease inhibitors for the treatment of HIV should carefully use the medication of Sildenafil Citrate. Protease inhibitors restrain the metabolism of sildenafil multiplying the plasma levels of sildenafil which increases the probability and severity of side-effects. Patients using Protease inhibitors are recommended not to use more than 25mg dose of Sildenafil Citrate every 48 hours.
By lowering the medications of Sildenafil Citrate the effects of blood pressure increases. Patients taking nitrates are not recommended to use Sildenafil Citrate because Sildenafil increases the blood pressure lowering the effects of nitrates.
Patients taking medications like Erythromycin Ketoconazole Nizoral Cimetidine Tagamet Mibefradil Posicor and Itraconazole Sporanox should be observed very carefully if Sildenafil is used because these medications can cause a drastic increase of Sildenafil in the body which can be harmful.

Uses
Sildenafil Citrate is primarily used for erectile dysfunction and pulmonary hypertension. Other than these it is also used for the prevention of Altitude sickness suffered by mountain climbers. It is also used for recreational use and in sports for enhancing performance. It is experimented on wilted plants too. A low-concentrated solution of sildenafil in water can significantly prolongs the time from 1 week to 2 weeks before cut flowers wilt.
Storage
Sildenafil Citrate should be stored at room temperature 15 to 30 Degree C 59 to 89 Degree F
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