Zanaflex [Tizanidine hydrochloride] is a short-action drug that is used in managing spasticity. This medication is not meant for long-term relief of the disease, rather it is prescribed for those times when relief from spasticity is important.
How to use
Zanaflex [Tizanidine hydrochloride] is a prescription drug that should be administered exactly as per the doctor’s instructions. One dose of 8 mg of the drug reduces the muscle tone of spastic patients for several hours. The effect is noticed about 1-2 hours after administration of the medication and goes away in 3-6 hours. Effects depend on the dose. Although a dosage of less than 8 mg has not been known to be effective in the studies conducted in controlled clinical trials, therapy is usually started with 4 mg because of the drug’s tendency to cause side effects in patients. The dosage is gradually increased to reach a level where the optimum effect is possible. If the doctor prescribes, the dose can be repeated every 6-8 hours. The maximum dosage for a day should never exceed 36 mg.
Side Effects
Zanaflex [Tizanidine hydrochloride] may cause side effects in patients. Common side effects that have been reported are constipation, drowsiness, weakness, dry mouth, dizziness and fatigue. In case any of these persist, notifying the doctor is necessary.
Serious but unlikely side effects of this drug are fainting, mood changes, hallucinations, blurred vision, burning sensation during passing of urine or too frequent urination.
Rare but very serious side effects of this drug are irregular heartbeat or black-colored stools. In case they do occur, the doctor should be called for immediately.
This drug has been known to cause life-threatening liver disease in very rare cases. Caregivers and family members should be vigilant about symptoms of liver disease occurring.
Drug Interaction
Zanaflex [Tizanidine hydrochloride] may cause drug interactions when administered in combination with other medications such as the ones mentioned below:
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe drowsiness, fainting, trouble breathing, or unconsciousness.
Notes
Your doctor may monitor liver tests during treatment. Do not share this medication with others.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Uses
Zanaflex [Tizanidine hydrochloride] is prescribed for the treatment of muscle spasms in spastic patients. It allows patients suffering from spinal injury or multiple sclerosis to experience an ease of pain and the improved ability to move around.
Storage
Zanaflex [Tizanidine hydrochloride] should be stored at 15-30°C.
Precaution
Zanaflex [Tizanidine hydrochloride] is not recommended for pregnant women and lactating mothers.
This drug should be prescribed with caution by patients with liver disease, high or low blood pressure, kidney disease or “Long QT syndrome”.
Consumption of alcohol should be stopped while therapy is on. Since this drug may cause drowsiness or blurred vision, patients on therapy should better not drive or operate heavy machinery.
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